melanoma相关论文
目的:探讨黑色素瘤肝转移的超声及临床病理特征。方法:选取2013—2019年于天津医科大学肿瘤医院诊治的13例黑色素瘤肝转移患者,回顾......
皮肤恶性黑色素瘤(CMM)是一种早期即可发生淋巴转移,预后严重不良的侵袭性恶性皮肤系统肿瘤。其淋巴转移机制非常复杂,涉及到细胞运动......
Objective:The morbidity of malignant melanoma keeps increasing annually.It has high risks of metastasis,drug resistance,......
目的:观察睫状体无色素上皮腺瘤(ANPCE)的超声影像特征。方法:回顾性病例对照研究。2014年1月至2021年10月于首都医科大学附属北京同......
目的:观察并分析葡萄膜黑色素瘤(UM)患者巩膜外敷贴放射治疗(PRT)的不同临床反应模式以及治疗失败后行二期眼球摘除手术的危险因素。方......
葡萄膜黑色素瘤(UM)是眼内侵袭性强且致命的肿瘤。由于UM及其微环境的复杂性和异质性,导致缺乏早期预防和治疗转移的策略。单细胞测序......
葡萄膜黑色素瘤(UM)是成人中最常见的原发性眼内恶性肿瘤。UM在亚洲地区的发病率低于欧美国家,但亚洲UM患者的发病年龄比欧美国家人群......
阴茎黑色素瘤临床少见。本文报道1例,患者因阴茎外伤20个月,发现阴茎肿物14个月入院,行阴茎肿物切除+左侧腹股沟淋巴结活检术,病理示阴......
Objective: Cellular heterogeneity is regarded as a major factor affecting treatment response and resistance in malignant......
目的:探讨基线n 18F-FDG PET/CT原发灶代谢参数对原发性恶性黑色素瘤的预后意义。n 方法:回顾性分析南京大学医学院附属......
Fast reaction and long duration-application of dabrafenib plus trametinib in treatment of metastatic
The prognosis of patients with advanced melanoma is poor.The five-year recurrence rate is approximately 70%,whereas the o......
Interleukins (ILs) and associated cytokines serve as the means of communication for immune cells and non-immune cells. T......
Melanoma,which is easy to metastasize distally,is the most aggressive of all human skin cancers and leads to approximate......
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Objective Melanoma is the main cause of death associated with skin cancer.Malignant melanoma(MM)is associated with skin ......
Purpose:To confirm whether flotillin 2 (FLOT2) is a direct target of miR-34a and miR-34a/FLOT2 pathway plays a key role ......
Objective Melanoma was the most malignant skin neoplasm with an increasing morbidity around the world.Although new immun......
Objective Melanoma is a relatively common,aggressive cutaneous cancer of increasing incidence that has a high mortality ......
Can non-sentinel lymph node(NSLN)positive melanoma be exempted from complete lymph node dissection(C
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Topical treatment of All-trans Retinoic Acid inhibits murine melanoma by promoting CD8+T and NK cell
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Transcriptional regulation of TGF-β1 combined with miR200c mimics increase therapeutic efficacy of t
The transforming growth factor β (TGF-β) in tumor environment can promote the upregulation of Zinc-finger E-box bindin......
IGFBP2 regulates PD-L1 expression through activation of the EGFR-STAT3 signaling pathway in malignan
Objective Immunotherapy by targeting the PD-1/PD-L1 receptor in melanoma patients has achieved a great success.Although ......
Objective To investigate the anticancer effect of doxorubicin loaded nanometer(DLN)with miR-21 inhibitor in melanoma,and......
Effectiveness and Safety of PD-1 Inhibitors in the Treatment against Solid Tumors: A Systematic Revi
目的 PD-1/PD-L1 inhibitors have been implicated as potentially effective anti-cancer therapies. Some clinical Randomized......
Objective Melanoma is the most aggressive type of skin cancer.Melanoma has an extremely poor prognosis because of its hi......
A Randomized Phase Ⅱ Study Evaluating the Activity of Bevacizumab in Combination With Carboplatin Pl
目的: Mucosal melanoma is rare in Caucasian population but account for 25% in Asian population.It is usually associated wi......
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Preliminary results of a phase Ⅱ trial with continuous intravenous infusion rh-Endostatin plus dacar
目的: A phase Ⅱ study has revealed that rh-Endostatin (Endostar) was more effective when combining with dacarbazine (DTI......
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Clinical presentation, systemic therapy and prognosis of mucosal melanoma, a study of 463 consecutiv
目的 : Mucosal melanoma (MM) is the second common subtype in Asians with a percentage of 22-25%;but there have been few epi......
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p-hydroxylcinnamaldehyde induces the differentiation of B16F1 melanoma cells via a GTP-Rho1-MAPKs pa
Aim of this study: The overall objective of the present study was to understand the differential effect of p-hydroxylcin......
Isophilippinolide A Arrests Cell Cycle Progression and Induces Apoptosis in Human Melanoma Cells for
Three new butanolides, isophilippinolide A, philippinolide A, philippinolide B, an amide, cinnaretamine were isolated fr......
An engineered PD-1-based and MMP-2/9-oriented fusion protein exerts potent antitumor efficacy agains
Recent studies have shown that PD-1/PD-L1 checkpoint blockade is a dramatic therapy for melanoma through enhancing antit......
Doxorubicin(DOX)is widely used in cancer therapy.However,its application is sometimes limited because of its adverse car......
Ovostatin 2 knockdown significantly inhibits the growth,migration,and tumorigenicity of cutaneous ma
We previously identified ovostatin 2 as a new candidate gene of cutaneous malignant melanoma in a Chinese population.In ......
Melanoma is a malignancy of melanocytes which are pigment-producing cells of neuroectodermal origin that can be found th......
Low concentration of caffeine inhibits cell viability,migration and invasion,and induces cell apopto
We aimed to explore the effects of low concentration of 1,3,7-trimethylxanthine(caffeine)on melanoma cells,as well as th......
目的: BRAF/NRAS mutations are predictors of poor prognosis in melanoma.High-dose interferon (HDI) is the only drug approv......
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目的: Everolimus, an oral mTOR inhibitor, has shown minimal activity as a single agent in patients with metastatic melano......
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Clinical response, progression-free survival(PFS), and safety in patients (pts) with advanced melano
Objective: Combined blockade of T-cell checkpoints by NIVO and IPI demonstrated a high objective response rate (ORR), pr......
Primary intramedullary melanoma associated with syringomyelia:apropos of a case,radiological diagnos
The case report describes a 50-year-old man with primary spinal cord malignant melanoma localized in the thoracic region......
为了探索一种智能、无损检测黑色素瘤边界的方法,开发了一套具有紧凑结构和自动化软件的光纤光谱仪系统,并将其应用于皮肤色素沉积的......
The contrast mechanism of different polarization imaging techniques for melanoma in mouse skin is studied using both exp......